Intellectual Property
DNE Technology
Precision takes its market-leading intellectual property position very seriously and has an extensive body of IP directed to its core meganuclease technology as well as applications for this technology. Precision's published patents and patent applications include:
US 8,021,867 RATIONALLY-DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY.
US 8,119,361 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
US 8,119,381 RATIONALLY-DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY.
US 8,124,369 METHODS OF CLEAVING DNA WITH
RATIONALLY-DESIGNED MEGANUCLEASES.
US 8,129,134 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
US 8,133,697 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
EP 2,357,226 RATIONALLY-DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY.
US 8,143,015 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
US 8,143,016 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
US 8,148,098 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
US 8,163,514 METHODS OF CLEAVING DNA WITH RATIONALLY-DESIGNED MEGANUCLEASES.
WO 2007/047859 RATIONALLY-DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY.
WO 2009/059195 RATIONALLY-DESIGNED SINGLE-CHAIN MEGANUCLEASES WITH NON-PALINDROMIC RECOGNITION SEQUENCES.
WO 2009/076292 RATIONALLY-DESIGNED MEGANUCLEASES WITH RECOGNITION SEQUENCES FOUND IN DNASE HYPERSENSITIVE REGIONS OF THE HUMAN GENOME.
WO 2009/114321 RATIONALLY-DESIGNED MEGANUCLEASES FOR MAIZE GENOME ENGINEERING.
WO 2009/134714 FUSION MOLECULES OF RATIONALLY-DESIGNED DNA-BINDING PROTEINS AND EFFECTOR DOMAINS.
WO 2010/009147 RECOGNITION SEQUENCES FOR I-CREI-DERIVED MEGANUCLEASES AND USES THEREOF.
US 12/403,093 TEMPERATURE-DEPENDANT MEGANUCLEASE ACTIVITY.
