Advantages of DNE


DNE Technology

Stability. Because DNE directly modifies the chromosomal DNA, genetic changes introduced by DNE are permanent and heritable.


Specificity. Because DNE is based on a natural genome-editing system, it offers the highest level of assurance that the intended site - and only the intended site - will be modified.


Traceless. DNE does not require the incorporation of selectable markers, vector sequences, or other extraneous DNA.


Speed. A DNE meganuclease can typically be custom made for a particular application in 2-6 weeks. A DNE-induced genetic modification can generally be made in 2-3 months, depending on cell type.


Versatility. DNE can be used to produce virtually any genetic modification in a wide range of cell types.


Proven. DNE has been validated in numerous plant and animal cell types by Precision and its external research partners.


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